Metalloproteinase Matrix Products Doxorubicin Conjugate Destruction For Delivery of Anticancer Drugs: Calorimetric, Spectroscopy, and Study of Molecular Dynamics on Peptides – Doxorubicin Binding to DNA
Matrix Metalloproteinases (MMPS) is a relegation factor of extracellular matrix, promoting cancer development. Therefore, they can provide shipping doxorubicin (DOX) which is assisted by enzymes in cancer treatment. In the current study, the DOX and Tetrapeptide-DoX intercalation process, products from MMPs division from the DOX Linked operators, into DSDNA are investigated using stationary fluorescence spectroscopy …