Medchemexpress Hy-101943 Ly 345899

LY 345899

HY-101943 10mg
EUR 2272.76
Description: LY 345899 is a Folate analog and is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inbhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 18 nM for MTHFD1[1][2][3].

Human IgG antibody Laboratories manufactures the medchemexpress hy-101943 ly 345899 reagents distributed by Genprice. The Medchemexpress Hy-101943 Ly 345899 reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact MedChemExpress Inc.. Other Medchemexpress products are available in stock. Specificity: Medchemexpress Category: Hy-101943 Group: Ly 345899

LY 345899

5x100mg
EUR 15760

LY 345899

100mg
EUR 2595

LY 345899

10mg
EUR 650

LY 345899

25mg
EUR 1215

LY 345899

50mg
EUR 1675

LY 345899

5mg
EUR 420

LY 345899

10mg Ask for price
Description: LY 345899

LY 345899

1g Ask for price
Description: LY 345899

LY 345899

1mg Ask for price
Description: LY 345899

LY 345899

50mg Ask for price
Description: LY 345899

LY 345899

5mg Ask for price
Description: LY 345899

Anti-Mouse Ly-6G and Ly-6C Antibody

0.1mg
EUR 310

Ly 345899 information

LY 345899

T15827-10mg 10mg Ask for price
Description: LY 345899

LY 345899

T15827-1g 1g Ask for price
Description: LY 345899

LY 345899

T15827-1mg 1mg Ask for price
Description: LY 345899

LY 345899

T15827-50mg 50mg Ask for price
Description: LY 345899

LY 345899

T15827-5mg 5mg Ask for price
Description: LY 345899

LY 344864

HY-13788 10mM/1mL
EUR 411.26
Description: LY 344864 is a selective, orally active 5-HT1F receptor agonist with a Ki of 6 nM. LY 344864 is a full agonist producing an effect similar in magnitude to serotonin itself. LY 344864 can cross the blood brain barrier to some extent[1].

LY-466195

HY-19858 Get quote Ask for price
Description: LY-466195 is a selective and competitive GLUK5 receptor antagonist. LY-466195 antagonizes Kainate-induced currents with an IC50 value of 0.045 μM in rat dorsal root ganglion neurons. In HEK293 cells transfected with GLUK5, GLUK2/GLUK5, or GLUK5/GLUK66 receptors, LY466195 produces IC50 values of 0.08 μM, 0.34 μM, and 0.07 μM, respectively[1].

LY-411575

HY-50752 100mg
EUR 571.44
Description: LY-411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), and also inhibits Notch S3 cleavage with IC50 of 0.39 nM.

LY 235959

HY-101353 Get quote Ask for price
Description: LY 235959 is a competitive N-methyl-D-aspartate (NMDA)-receptor antagonist. LY 235959 potentiates the anticonvulsant action of antiepileptics[1].

LY 178002

HY-101579 1mg
EUR 391.2
Description: LY 178002 is a potent inhibitor of 5-lipoxygenase (5-LPO), phospholipase A2, with IC50 of 0.6 μM for 5-lipoxygenase, inhibits cellular production of LTB4 by human polymorphonuclear leukocytes, and shows relatively weak inhibition on cyclooxygenase.

LY 2033298

HY-101841 Get quote Ask for price
Description: LY 2033298 is a selective positive allosteric modulator of the muscarinic M4 receptor. LY 2033298 can be used in the study of psychiatric disorders[1].

LY-517717

HY-10269 Get quote Ask for price
Description: LY-517717 is a potent and orally active FXa inhibitor. LY-517717 shows antithrombotic and anticoagulant activity. LY-517717 has the potential for the research of venous thromboembolism after hip or knee replacement[1].

LY 541850

HY-103551A Get quote Ask for price
Description: LY 541850 is claimed from human ionotropic and metabotropic glutamate (mGlu) receptors expressed in non-neuronal cells. LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively[1].

LY-311727

HY-107393 5 mg
EUR 303.04
Description: LY-311727 is a potent secretory non-pancreatic phospholipase A2 (sPLA2) inhibitor (IC50 <1 μM for group IIA sPLA2). sPLA2 is an important proinflammatory enzyme[1][2].

LY-2087101

HY-107683 Get quote Ask for price
Description: LY-2087101 is an allosteric potentiator of α7 nAChRs. LY-2087101 causes potentiation of agonist-evoked α7 responses by binding within the nAChR transmembrane region[1].

LY 233053

HY-107710 Get quote Ask for price
Description: LY 233053 is a potent and competitive NMDA-receptor antagonist with anticonvulsant and antiepileptic efficacy[1][2].

LY-3381916

HY-111540 10mM/1mL
EUR 476.2
Description: LY-3381916 (IDO1-IN-5) is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].

LY 163443

HY-113758 Get quote Ask for price
Description: LY 163443 is a selective antagonist of leukotrienes D4 (LTD4) and E4 (LTE4). LY 163443 can antagonize LTD4-induced contractions of guinea pig ileum, trachea, and lung parenchyma. LY 163443 also inhibits tracheal contractions to LTE4[1][2].

LY 3000328

HY-15533 5mg
EUR 1028.15
Description: LY 3000328 (Z-FL-COCHO) is a potent and selective Cathepsin S (Cat S) inhibitor with IC50s of 7.7 and 1.67 nM for hCat S and mCat S, respectively.

LY 303511

HY-15643 50mg
EUR 1166.4
Description: LY303511 is a structural analogue of LY294002. LY303511 does not inhibit PI3K. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells. LY303511 reversibly blocks K+ currents (IC50=64.6±9.1 μM) in MIN6 insulinoma cells.

LY 295427

HY-125544 Get quote Ask for price
Description: LY 295427 is a LDL receptor modulator and a hypocholesterolemic agent. LY 295427 derepresses the transcription of the LDLR (LDL Receptor). LY 295427 can be used for hypercholesterolemia research[1][2][3].

LY-338979

HY-125691 1 mg
EUR 468.62
Description: LY-338979 (Pemetrexed 6-oxo diacid impurity) is a metabolite of LY231514 (Pemetrexed; HY-10820)[1].

LY-404187

HY-13456 10 mg
EUR 108.23
Description: LY-404187 is a potent, selective and centrally active positive allosteric modulator of AMPA receptors, with the EC50s of 5.65, 0.15, 1.44, 1.66 and 0.21 µM for GluR1i, GluR2i, GluR2o, GluR3i and GluR4i, respectively. LY-404187 has therapeutic potential in a number of psychiatric disorders and neurodegenerative diseases[1][2].

LY-364947

HY-13462 50mg
EUR 354.98
Description: LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM, and exhibits 7-fold selectivity over TGFβR-II[1].

LY-402913

HY-117452 Get quote Ask for price
Description: LY-402913 is a selective multidrug resistance protein (MRP1) inhibitor[1].

LY 292728

HY-117706 Get quote Ask for price
Description: LY 292728 is a potent leukotriene B4 (LTB4) receptor antagonist. LY 292728 binds to human neutrophils with a Ki of 0.47 nM and binds to guinea pig lung membranes with a Ki of 0.04 nM[1].

LY 97241

HY-119211 Get quote Ask for price
Description: LY 97241 accelerates the apparent rate of inactivation of transient outward K current. LY 97241 is an antiarrhythmic drug[1].

LY 233536

HY-120189 Get quote Ask for price
Description: LY 233536 is a competitive NMDA receptor antagonist[1].