Medchemexpress Hy-101943 Ly 345899

LY 345899

HY-101943 10mg
EUR 2272.76
Description: LY 345899 is a Folate analog and is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inbhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 18 nM for MTHFD1[1][2][3].

Human IgG antibody Laboratories manufactures the medchemexpress hy-101943 ly 345899 reagents distributed by Genprice. The Medchemexpress Hy-101943 Ly 345899 reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact MedChemExpress Inc.. Other Medchemexpress products are available in stock. Specificity: Medchemexpress Category: Hy-101943 Group: Ly 345899

LY 345899

5mg
EUR 420

LY 345899

10mg Ask for price
Description: LY 345899

LY 345899

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Description: LY 345899

LY 345899

1mg Ask for price
Description: LY 345899

LY 345899

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Description: LY 345899

LY 345899

5mg Ask for price
Description: LY 345899

Anti-Mouse Ly-6G and Ly-6C Antibody

0.1mg
EUR 310

Ly 345899 information

LY 233536

HY-120189 Get quote Ask for price
Description: LY 233536 is a competitive NMDA receptor antagonist[1].

LY 215890

HY-120382 Get quote Ask for price
Description: LY 215890 ia an orally active antibacterial agent aganist Escherichia coli EC14 and Klebsiella pneumonia X26[1].

LY 293284

HY-120396 Get quote Ask for price
Description: LY 293284 is a potent and selective 5-HT1A receptor agonist. LY 293284 results in a significant drop in core temperature and consumes more food in cholestasis rat induced by bile duct resection[1][2].

LY-404187

HY-13456 10 mg
EUR 108.23
Description: LY-404187 is a potent, selective and centrally active positive allosteric modulator of AMPA receptors, with the EC50s of 5.65, 0.15, 1.44, 1.66 and 0.21 µM for GluR1i, GluR2i, GluR2o, GluR3i and GluR4i, respectively. LY-404187 has therapeutic potential in a number of psychiatric disorders and neurodegenerative diseases[1][2].

LY-364947

HY-13462 50mg
EUR 354.98
Description: LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM, and exhibits 7-fold selectivity over TGFβR-II[1].

LY 344864

HY-13788 10mM/1mL
EUR 411.26
Description: LY 344864 is a selective, orally active 5-HT1F receptor agonist with a Ki of 6 nM. LY 344864 is a full agonist producing an effect similar in magnitude to serotonin itself. LY 344864 can cross the blood brain barrier to some extent[1].

LY 3000328

HY-15533 5mg
EUR 1028.15
Description: LY 3000328 (Z-FL-COCHO) is a potent and selective Cathepsin S (Cat S) inhibitor with IC50s of 7.7 and 1.67 nM for hCat S and mCat S, respectively.

LY 303511

HY-15643 50mg
EUR 1166.4
Description: LY303511 is a structural analogue of LY294002. LY303511 does not inhibit PI3K. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells. LY303511 reversibly blocks K+ currents (IC50=64.6±9.1 μM) in MIN6 insulinoma cells.

LY-411575

HY-50752 100mg
EUR 571.44
Description: LY-411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), and also inhibits Notch S3 cleavage with IC50 of 0.39 nM.

LY-466195

HY-19858 Get quote Ask for price
Description: LY-466195 is a selective and competitive GLUK5 receptor antagonist. LY-466195 antagonizes Kainate-induced currents with an IC50 value of 0.045 μM in rat dorsal root ganglion neurons. In HEK293 cells transfected with GLUK5, GLUK2/GLUK5, or GLUK5/GLUK66 receptors, LY466195 produces IC50 values of 0.08 μM, 0.34 μM, and 0.07 μM, respectively[1].

LY 178002

HY-101579 1mg
EUR 391.2
Description: LY 178002 is a potent inhibitor of 5-lipoxygenase (5-LPO), phospholipase A2, with IC50 of 0.6 μM for 5-lipoxygenase, inhibits cellular production of LTB4 by human polymorphonuclear leukocytes, and shows relatively weak inhibition on cyclooxygenase.

LY 2033298

HY-101841 Get quote Ask for price
Description: LY 2033298 is a selective positive allosteric modulator of the muscarinic M4 receptor. LY 2033298 can be used in the study of psychiatric disorders[1].

LY-517717

HY-10269 Get quote Ask for price
Description: LY-517717 is a potent and orally active FXa inhibitor. LY-517717 shows antithrombotic and anticoagulant activity. LY-517717 has the potential for the research of venous thromboembolism after hip or knee replacement[1].

LY 541850

HY-103551A Get quote Ask for price
Description: LY 541850 is claimed from human ionotropic and metabotropic glutamate (mGlu) receptors expressed in non-neuronal cells. LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively[1].

LY-311727

HY-107393 5 mg
EUR 303.04
Description: LY-311727 is a potent secretory non-pancreatic phospholipase A2 (sPLA2) inhibitor (IC50 <1 μM for group IIA sPLA2). sPLA2 is an important proinflammatory enzyme[1][2].

LY-2087101

HY-107683 Get quote Ask for price
Description: LY-2087101 is an allosteric potentiator of α7 nAChRs. LY-2087101 causes potentiation of agonist-evoked α7 responses by binding within the nAChR transmembrane region[1].

LY 233053

HY-107710 Get quote Ask for price
Description: LY 233053 is a potent and competitive NMDA-receptor antagonist with anticonvulsant and antiepileptic efficacy[1][2].