LY 345899 |
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HY-101943 |
MedChemExpress |
10mg |
EUR 2272.76 |
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Description: LY 345899 is a Folate analog and is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inbhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 18 nM for MTHFD1[1][2][3]. |
Human IgG antibody Laboratories manufactures the medchemexpress hy-101943 ly 345899 reagents distributed by Genprice. The Medchemexpress Hy-101943 Ly 345899 reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact MedChemExpress Inc.. Other Medchemexpress products are available in stock. Specificity: Medchemexpress Category: Hy-101943 Group: Ly 345899
Anti-Mouse Ly-6G and Ly-6C Antibody |
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MyBiosource |
0.1mg |
EUR 310 |
Ly 345899 information
LY 344864 |
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HY-13788 |
MedChemExpress |
10mM/1mL |
EUR 411.26 |
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Description: LY 344864 is a selective, orally active 5-HT1F receptor agonist with a Ki of 6 nM. LY 344864 is a full agonist producing an effect similar in magnitude to serotonin itself. LY 344864 can cross the blood brain barrier to some extent[1]. |
LY-466195 |
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HY-19858 |
MedChemExpress |
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Description: LY-466195 is a selective and competitive GLUK5 receptor antagonist. LY-466195 antagonizes Kainate-induced currents with an IC50 value of 0.045 μM in rat dorsal root ganglion neurons. In HEK293 cells transfected with GLUK5, GLUK2/GLUK5, or GLUK5/GLUK66 receptors, LY466195 produces IC50 values of 0.08 μM, 0.34 μM, and 0.07 μM, respectively[1]. |
LY-411575 |
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HY-50752 |
MedChemExpress |
100mg |
EUR 571.44 |
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Description: LY-411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), and also inhibits Notch S3 cleavage with IC50 of 0.39 nM. |
LY 235959 |
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HY-101353 |
MedChemExpress |
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Description: LY 235959 is a competitive N-methyl-D-aspartate (NMDA)-receptor antagonist. LY 235959 potentiates the anticonvulsant action of antiepileptics[1]. |
LY 178002 |
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HY-101579 |
MedChemExpress |
1mg |
EUR 391.2 |
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Description: LY 178002 is a potent inhibitor of 5-lipoxygenase (5-LPO), phospholipase A2, with IC50 of 0.6 μM for 5-lipoxygenase, inhibits cellular production of LTB4 by human polymorphonuclear leukocytes, and shows relatively weak inhibition on cyclooxygenase. |
LY 2033298 |
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HY-101841 |
MedChemExpress |
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Description: LY 2033298 is a selective positive allosteric modulator of the muscarinic M4 receptor. LY 2033298 can be used in the study of psychiatric disorders[1]. |
LY-517717 |
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HY-10269 |
MedChemExpress |
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Description: LY-517717 is a potent and orally active FXa inhibitor. LY-517717 shows antithrombotic and anticoagulant activity. LY-517717 has the potential for the research of venous thromboembolism after hip or knee replacement[1]. |
LY 541850 |
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HY-103551A |
MedChemExpress |
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Description: LY 541850 is claimed from human ionotropic and metabotropic glutamate (mGlu) receptors expressed in non-neuronal cells. LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively[1]. |
LY-311727 |
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HY-107393 |
MedChemExpress |
5 mg |
EUR 303.04 |
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Description: LY-311727 is a potent secretory non-pancreatic phospholipase A2 (sPLA2) inhibitor (IC50 <1 μM for group IIA sPLA2). sPLA2 is an important proinflammatory enzyme[1][2]. |
LY-2087101 |
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HY-107683 |
MedChemExpress |
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Description: LY-2087101 is an allosteric potentiator of α7 nAChRs. LY-2087101 causes potentiation of agonist-evoked α7 responses by binding within the nAChR transmembrane region[1]. |
LY 233053 |
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HY-107710 |
MedChemExpress |
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Description: LY 233053 is a potent and competitive NMDA-receptor antagonist with anticonvulsant and antiepileptic efficacy[1][2]. |
LY-3381916 |
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HY-111540 |
MedChemExpress |
10mM/1mL |
EUR 476.2 |
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Description: LY-3381916 (IDO1-IN-5) is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1]. |
LY 163443 |
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HY-113758 |
MedChemExpress |
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Description: LY 163443 is a selective antagonist of leukotrienes D4 (LTD4) and E4 (LTE4). LY 163443 can antagonize LTD4-induced contractions of guinea pig ileum, trachea, and lung parenchyma. LY 163443 also inhibits tracheal contractions to LTE4[1][2]. |
LY 3000328 |
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HY-15533 |
MedChemExpress |
5mg |
EUR 1028.15 |
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Description: LY 3000328 (Z-FL-COCHO) is a potent and selective Cathepsin S (Cat S) inhibitor with IC50s of 7.7 and 1.67 nM for hCat S and mCat S, respectively. |
LY 303511 |
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HY-15643 |
MedChemExpress |
50mg |
EUR 1166.4 |
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Description: LY303511 is a structural analogue of LY294002. LY303511 does not inhibit PI3K. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells. LY303511 reversibly blocks K+ currents (IC50=64.6±9.1 μM) in MIN6 insulinoma cells. |
LY 295427 |
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HY-125544 |
MedChemExpress |
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Description: LY 295427 is a LDL receptor modulator and a hypocholesterolemic agent. LY 295427 derepresses the transcription of the LDLR (LDL Receptor). LY 295427 can be used for hypercholesterolemia research[1][2][3]. |
LY-338979 |
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HY-125691 |
MedChemExpress |
1 mg |
EUR 468.62 |
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Description: LY-338979 (Pemetrexed 6-oxo diacid impurity) is a metabolite of LY231514 (Pemetrexed; HY-10820)[1]. |
LY-404187 |
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HY-13456 |
MedChemExpress |
10 mg |
EUR 108.23 |
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Description: LY-404187 is a potent, selective and centrally active positive allosteric modulator of AMPA receptors, with the EC50s of 5.65, 0.15, 1.44, 1.66 and 0.21 µM for GluR1i, GluR2i, GluR2o, GluR3i and GluR4i, respectively. LY-404187 has therapeutic potential in a number of psychiatric disorders and neurodegenerative diseases[1][2]. |
LY-364947 |
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HY-13462 |
MedChemExpress |
50mg |
EUR 354.98 |
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Description: LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM, and exhibits 7-fold selectivity over TGFβR-II[1]. |
LY-402913 |
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HY-117452 |
MedChemExpress |
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Description: LY-402913 is a selective multidrug resistance protein (MRP1) inhibitor[1]. |
LY 292728 |
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HY-117706 |
MedChemExpress |
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Description: LY 292728 is a potent leukotriene B4 (LTB4) receptor antagonist. LY 292728 binds to human neutrophils with a Ki of 0.47 nM and binds to guinea pig lung membranes with a Ki of 0.04 nM[1]. |
LY 97241 |
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HY-119211 |
MedChemExpress |
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Description: LY 97241 accelerates the apparent rate of inactivation of transient outward K current. LY 97241 is an antiarrhythmic drug[1]. |
LY 233536 |
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HY-120189 |
MedChemExpress |
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Description: LY 233536 is a competitive NMDA receptor antagonist[1]. |
