Antitumor effects and molecular mechanisms of natural product actions in ovarian cancer

Antitumor effects and molecular mechanisms of natural product actions in ovarian cancer

Ovarian cancer is a general malignancy and the second causes of the second mortality among women with genital cancer. At present, postoperative platinum drugs and paclitaxel-based chemotherapy is the treatment of gold standard for ovarian cancer. However, patients who accept these chemotherapy often experience cumulative and susceptible toxic effects on chemotherapy resistance. Therefore, it is necessary to determine the more effective treatment options that will be tolerated by the patient.

Recent studies have reported the therapeutic effects of various natural products in patients with ovarian cancer. In particular, this natural ingredient does not induce bad effects on healthy cells and networks, indicating that natural products can function as a safe alternative treatment for ovarian cancer. The antitumor effect of natural products is associated with cell proliferation oppression and metastasis, autophagy stimulation, increased chemotherapy sensitivity, and apoptosis induction.

This review focuses on the effects of antitumor from several natural products, including curcumin, resveratrol, ginsenosides, (-) – epigallocatechin-3-gallate and quercetin, which is increasingly investigated as a therapeutic option in ovarian cancer, and discusses the molecular mechanism involved in cell proliferation, apoptosis, autophagy, metastasis and sensitization.

Diseasal disinfection disinfection of precursor products from UK lowland surface water: molecular weight and bromide

The study currently compares the impact of three different unit processes, coagulation, granular activated carbon (GAC), and novels suspended ion exchange technology (six), in disinfection with the potential formation of a by-product (DBPFP) of two British lowland water sources with medium For high bromide content. Special attention is given to the influence of organic molecular weight (MW) in DBPFP and the impact of bromide concentration. While some studies have investigated the impact of the MW fraction of liquid chromatography with an analysis of organic carbon detection (LC-OCD) in the elimination of dissolved organic carbon (DOC) with a different process, no one studies the effect of the MW doc fraction of this DBP analysis.

The impact of higher bromide concentrations is to reduce the total concentration of trihalomethane mass (THM) and haloacetic (HAA), in contrast to previous reported studies. The results showed that for the source of moderate bromide concentration (135 μg / L), the potential for THM formation was reduced by 22% or 64% after coagulation or six treatments. For high bromide content sources (210 μg / L), the elimination of the potential THM formation is 47% or 69% respectively after GAC or six treatments.

The trend was the same for Haas, although with a larger difference between two processes / feedwaters with reference to the overall removal. Statistical analysis shows that organic material MW> 350 g / mol has a significant impact on DBPFP. A multiple linear regression of the MW faction against DBPFP showed a strong correlation (R2 between 0.90 and 0.93), indicating that LC-OCD analysis could only be used to predict DBP formation with reasonable accuracy, and offering potential risk assessment fast source.

Putatatat SARS-COV-2 M Pro Inhibitors from the In-House Library of Natural Products and Nature-Inspired: Virtual Screening and Molecular Docking Studies

New Coronavirus (severe acute respiratory syndrome Coronavirus 2, SARS-COV-2) has been the cause of recent global pandemic. A very contagious nature of this life-threatening virus makes it very important to find therapy to ward off diffusion. The main protease (MPRO) SARS-COV-2 is a promising target of the drug because of its very necessary role in virus replication in the host. Using a combined two-step approach from virtual screening and molecular docking techniques, we have filtered small molecular in-house collections, especially consisting of natural compounds and nature inspired. Molecules are chosen with high structural diversity to close various chemical space into an enzyme bag. Virtual screening experiments are carried out using automodock vina software docking mode.

Antitumor effects and molecular mechanisms of natural product actions in ovarian cancer

Virtual playback allows the selection of structural heterogeneous compounds that are able to interact effectively with the SARS-COV-2 MPRO enzymatic site. Compounds that show the best interaction with printed proteins by molecular docking as implemented in Autodock, while complex stability is tested by molecular dynamics. The most promising candidate reveals good ability to enter into a protein binding pocket and to reach two catalytic numbers. There is a high probability that at least one of the selected scaffes can promise for further research.

Evaluating platelet activation related to biomaterial degradation products using molecular markers

The increasing number of biodegradable medical devices can be used in the circulatory system. The effects of relegation products released from this medical device on blood may be gradual and cumulative. When they reach a critical level, they can cause thrombosis and other complications. For this reason, it is important to evaluate blood compatibility of relegation products for quality control and development of this device. In this study, we evaluated the relegation products of four biodegradable materials (collagen, polylactic acid, calcium phosphate ceramics, and magnesium) using molecular markers of thrombosis activation associated with thrombosis.

Silica Gel Grade 408 12-24 Mesh

S02577 500G
EUR 255.5

Silica Gel Grade 40 -6+12 Mesh (1680-3350 microns)

S02572 250G
EUR 138.5

Silica Gel

17091-55 500G
EUR 12.25

Silica Gel

17092-45 500G
EUR 19.6

Silica Gel

30615-85 500G
EUR 19.6

Silica Gel

30619-45 500G
EUR 19.6

Silica gel

GRM151-1KG 1 unit
EUR 11.28
Description: Silica gel

Silica gel

GRM151-500G 1 unit
EUR 6.93
Description: Silica gel

Silica gel

GRM151-5KG 1 unit
EUR 50.46
Description: Silica gel

Silica Gel 60

30721-01 1KG
EUR 81.9

Silica Gel 60

30721-14 5KG
EUR 298.9

Silica Gel 60

30721-85 500G
EUR 49

Silica Gel 60

30724-55 500G
EUR 27.3

Silica Gel 60

30724-71 1KG
EUR 49.7

Silica Gel 60

30724-84 5KG
EUR 205.1

Silica gel H

GRM602-500G 1 unit
EUR 10.29
Description: Silica gel H

Silicon carbide 400 mesh

GRM7488-1KG 1 unit
EUR 70.04
Description: Silicon carbide 400 mesh

Silicon carbide 400 mesh

GRM7488-250G 1 unit
EUR 18.94
Description: Silicon carbide 400 mesh

Silica gel GF 254

GRM367-500G 1 unit
EUR 64.32
Description: Silica gel GF 254

Silica Gel 120, spherical

30734-41 1KG
EUR 56.7

Silica Gel 60, spherical

30731-42 25KG
EUR 957.6

Silica Gel 60, spherical

30731-71 1KG
EUR 51.8

Drying Reagent, Silica Gel

DSG110 1Kg
EUR 91.32

Silica gel G For TLC

GRM7480-500G 1 unit
EUR 10.87
Description: Silica gel G For TLC

Silica Gel with 3% AgNO3

S450270 10g
EUR 800

Silica gel HF 254 For TLC

GRM7482-500G 1 unit
EUR 70.56
Description: Silica gel HF 254 For TLC

Silica Gel 60, spherical, neutral

30511-06 5KG
EUR 343

Silica Gel 60, spherical, neutral

30511-22 25KG
EUR 1540

Silica Gel 60, spherical, neutral

30511-35 500G
EUR 57.4

Silica Gel 60, spherical, neutral

30511-51 1KG
EUR 98

Silica Gel 60, spherical, neutral

30511-64 100G
EUR 21

Silica Gel 60, spherical, neutral

30518-65 500G
EUR 42

Silica Gel 60, spherical, neutral

30518-81 1KG
EUR 66.5

Silica Gel 60, spherical, neutral

30518-94 100G
EUR 17.5

Silica Gel, 40-63 Micron Particles

S450200 1kg
EUR 787
Description: 112926-00-8

Silica Gel, 35-70 Micron Particles

S450400 2.5kg
EUR 667
Description: 112926-00-6

Silica gel orange 360 g - EACH

DD490938 EACH
EUR 87.75

Silica Gel Large Pore 70 microns

S02580 100G
EUR 118.9

Silica Gel In Bag, 5G, 100/Pk

DSG111 1PK, 100UNIT
EUR 73.57

Silica Gel Grade 12 High Purity Chromatographic Gel 28-20

S02571 1KG
EUR 163.9

5g Silica Gel Sachets In Tyvek - PK1000

X17976 PK1000
EUR 130.72

3-Aminopropyl-funtionalized Silica Gel (40-63 μm)

A450215 1g
EUR 132

Silica Gel Grade 923 High Purity Chromatographic_x000D_

S02578 100G
EUR 278.15

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254-1 1
EUR 47.4

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254-1KG 1 kg
EUR 93.6

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254-5 5
EUR 174

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254-500 500
EUR 27.8

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254-500G 500 g
EUR 69.6

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254-5KG 5 kg
EUR 246

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287-1 1
EUR 47.4

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287-1KG 1 kg
EUR 93.6

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287-5 5
EUR 174

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287-500 500
EUR 27.8

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287-500G 500 g
EUR 69.6

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287-5KG 5 kg
EUR 246

C18 Silica Gel (>10% C-18; Capped With TMS)

S452500 50g
EUR 265

Silica gel, pore size 60A, particle size 40-63 micron

GX9977-1 1
EUR 54.4

Silica gel, pore size 60A, particle size 40-63 micron

GX9977-1KG 1 kg
EUR 102

Silica Gel, self-indicating, blue to pink, 2 - 5 mm beads

GE5162-1 1
EUR 58.4

Silica Gel, self-indicating, blue to pink, 2 - 5 mm beads

GE5162-1KG 1 kg
EUR 106.8

Silica Gel, self-indicating, blue to pink, 2 - 5 mm beads

GE5162-5 5
EUR 213.7

Silica Gel, self-indicating, blue to pink, 2 - 5 mm beads

GE5162-500 500
EUR 33.1

Silica Gel, self-indicating, blue to pink, 2 - 5 mm beads

GE5162-500G 500 g
EUR 76.8

Silica Gel, self-indicating, blue to pink, 2 - 5 mm beads

GE5162-5KG 5 kg
EUR 294

DiagNano Silica Particles, 400 nm

DNG-B008 10 mL
EUR 670.8

Silicon carbide 220 mesh

GRM7487-1KG 1 unit
EUR 84.04
Description: Silicon carbide 220 mesh

Silicon carbide 220 mesh

GRM7487-250G 1 unit
EUR 24.12
Description: Silicon carbide 220 mesh

Silicon powder 99.999% -325 Mesh

S02610 25G
EUR 409.38

Silicon carbide 99% -100 Mesh

S02620 500G
EUR 209.5

Silicon dioxide 99.5% -325 MESH

S02645 250G
EUR 159.75

Silicon(IV) oxide, 99.99%, -100 mesh

GX8518-250 250
EUR 356.8

Silicon(IV) oxide, 99.99%, -100 mesh

GX8518-50 50
EUR 140.2

Silica Gel, self-indicating, orange to colourless, 4 - 8 mm beads, cobalt free

GE9411-1 1
EUR 60.1

Silica Gel, self-indicating, orange to colourless, 4 - 8 mm beads, cobalt free

GE9411-1KG 1 kg
EUR 109.2

Silica Gel, self-indicating, orange to colourless, 4 - 8 mm beads, cobalt free

GE9411-500 500
EUR 35.5

Silica Gel, self-indicating, orange to colourless, 4 - 8 mm beads, cobalt free

GE9411-500G 500 g
EUR 79.2

Foil pouch and silica gel pack for storage of microtitre (ELISA) plates (10 pcs)

100191 10 pcs
EUR 22
Description: Foil pouch and silica gel pack for storage of microtitre (ELISA) plates (10 pcs)

Silicon nitride -325 or -2500 mesh sizes

S02660 10G
EUR 162.21

Silicon Powder -100, +325 mesh, amorphous, 99.999%

GX3061-250 250
EUR 840.8

Silicon Powder -100, +325 mesh, amorphous, 99.999%

GX3061-50 50
EUR 236.2

MagIso™ cfDNA Silica Magnetic Particles, 400 nm

WHK-C031 10 ml
EUR 625

Silica

si300 2 ML
EUR 367.5

DiagNano™ Plain Silica Particles, Nonporous, 400 nm, Powder

DNG-GS355 5 g
EUR 1160

Bromoacetyl resin (200-400 mesh)

4029092.0005 5 g
EUR 317.94

Bromoacetyl resin (200-400 mesh)

D-2555.0001 1.0g
EUR 166.8

Bromoacetyl resin (200-400 mesh)

D-2555.0005 5.0g
EUR 529.2

DiagNano™ PEI Mesoporous Silica Nanoparticles, 50 nm

WHM-23DN27 5 mL
EUR 1600

DiagNano™ PEI Mesoporous Silica Nanoparticles, 100 nm

WHM-23DN45 5 mL
EUR 1600

DiagNano™ Carboxyl Mesoporous Silica Particles, 3 μm

DNG-C046 10 mL
EUR 1275

DiagNano™ Plain Mesoporous Silica Nanoparticles, 50 nm

WHM-23DN23 5 mL
EUR 1160

DiagNano™ Amine Mesoporous Silica Nanoparticles, 50 nm

WHM-23DN25 5 mL
EUR 1220

DiagNano™ Thiol Mesoporous Silica Nanoparticles, 50 nm

WHM-23DN29 5 mL
EUR 1600

DiagNano™ Plain Mesoporous Silica Nanoparticles, 100 nm

WHM-23DN41 5 mL
EUR 1160

DiagNano™ Amine Mesoporous Silica Nanoparticles, 100 nm

WHM-23DN43 5 mL
EUR 1220

DiagNano™ Thiol Mesoporous Silica Nanoparticles, 100 nm

WHM-23DN47 5 mL
EUR 1600

DiagNano™ S-S Mesoporous Silica Nanoparticles, 50 nm

WHM-23DN28 5 mL
EUR 1600

DiagNano™ S-S Mesoporous Silica Nanoparticles, 100 nm

WHM-23DN46 5 mL
EUR 1600

DiagNano™ Li Ion Silica Particles, Nonporous, 400 nm, Powder

DNG-GS356 5 g
EUR 1160

DiagNano™ Carboxyl Mesoporous Silica Nanoparticles, 50 nm

WHM-23DN24 5 mL
EUR 1220

DiagNano™ Carboxyl Mesoporous Silica Nanoparticles, 100 nm

WHM-23DN42 5 mL
EUR 1220

Dowex® 50WX2, 200-400 mesh

RM2810-250G 1 unit
EUR 273.58
Description: Dowex® 50WX2, 200-400 mesh

Dowex® 50WX8, 200-400 mesh

RM2815-250G 1 unit
EUR 424.54
Description: Dowex® 50WX8, 200-400 mesh

DiagNano™ PEG Carboxyl Mesoporous Silica Nanoparticles, 50 nm

WHM-23DN26 5 mL
EUR 1600

DiagNano™ PEG Carboxyl Mesoporous Silica Nanoparticles, 100 nm

WHM-23DN44 5 mL
EUR 1600

Grids - Carbon Coated - Copper 400 mesh

24948-100 100EA
EUR 569

Grids - Carbon Coated - Copper 400 mesh

24948-25 25EA
EUR 154

Grids - Carbon Coated - Copper 400 mesh

24948-50 50EA
EUR 285

Flash Silica 120g - PK5

CHR5204 PK5
EUR 152.55

DiagNano™ Li Ion Silica Particles, Nonporous, 400 nm, Ethanol Dispersion

DNG-GS370 2 ml
EUR 1060

Flash Silica 330g - EACH

CHR5208 EACH
EUR 124.2

DiagNano™ Mesoporous Silica Coated Upconverting Nanoparticles, 365 nm

DNL-S006 10 mg
EUR 1780

DiagNano™ Mesoporous Silica Coated Upconverting Nanoparticles, 475 nm

DNL-S007 10 mg
EUR 1780

DiagNano™ Mesoporous Silica Coated Upconverting Nanoparticles, 545 nm

DNL-S008 10 mg
EUR 1780

DiagNano™ Mesoporous Silica Coated Upconverting Nanoparticles, 660 nm

DNL-S009 10 mg
EUR 1780

DiagNano™ Mesoporous Silica Coated Upconverting Nanoparticles, 804 nm

DNL-S010 10 mg
EUR 1780

DiagNano™ SBA-15 Mesoporous Silica Particles, 100 μm, 40 A Pore Size

DNG-GS379 5 g
EUR 960

DiagNano™ SBA-15 Mesoporous Silica Particles, 100 μm, 60 A Pore Size

DNG-GS380 5 g
EUR 960

DiagNano™ SBA-15 Mesoporous Silica Particles, 100 μm, 80 A Pore Size

DNG-GS381 5 g
EUR 960

DiagNano™ SBA-15 Mesoporous Silica Particles, 100 μm, 100 A Pore Size

DNG-GS382 5 g
EUR 960

DiagNano™ SBA-15 Mesoporous Silica Particles, 100 μm, 120 A Pore Size

DNG-GS383 5 g
EUR 960

DiagNano™ SBA-16 Mesoporous Silica Particles, 10 μm, 60 A Pore Size

DNG-GS384 5 g
EUR 960

DiagNano™ MCM-41 Mesoporous Silica Particles, 100 μm, 25 A Pore Size

DNG-GS399 5 g
EUR 960

DiagNano™ MCM-41 Mesoporous Silica Particles, 100 μm, 30 A Pore Size

DNG-GS402 5 g
EUR 960

DiagNano™ MCM-48 Mesoporous Silica Particles, 10 μm, 25 A Pore Size

DNG-GS406 5 g
EUR 960

DiagNano™ MCM-48 Mesoporous Silica Particles, 150 μm, 30 A Pore Size

DNG-GS409 5 g
EUR 960

DiagNano™ PEI Monodisperse Mesoporous Silica Nanoparticles, Hollow, 150 nm

WHM-23DN06 5 mL
EUR 2100

DiagNano™ PEI Monodisperse Mesoporous Silica Nanoparticles, Hollow, 350 nm

WHM-23DN13 5 mL
EUR 2100

Prefilled 2.0mL tubes 0.1mm Silica 1.4mm Zr 4mm Silica Bead 50pk - PK50

HOM3038 PK50
EUR 265.95

Silica Microspheres, 0.15µm

24320-15 15ml
EUR 514

Silica Microspheres, 0.30µm

24321-15 15ml
EUR 514

Silica Microspheres, 0.40µm

24322-15 15ml
EUR 514

Silica Microspheres, 0.50µm

24323-15 15ml
EUR 514

Silica Microspheres, 0.70µm

24324-15 15ml
EUR 618

Silica Microspheres, 0.90µm

24325-15 15ml
EUR 618

Silica Microspheres, 1.0µm

24326-15 15ml
EUR 618

Silica Microspheres, 1.5µm

24327-15 15ml
EUR 734

Silica Microspheres, 2.0µm

24328-15 15ml
EUR 734

Silica Microspheres, 2.5µm

24329-15 15ml
EUR 734

Silica Microspheres, 3.0µm

24330-15 15ml
EUR 865

Silica Microspheres, 4.0µm

24331-15 15ml
EUR 865

Silica Microspheres, 5.0µm

24332-15 15ml
EUR 865

DiagNano™ S-S Monodisperse Mesoporous Silica Nanoparticles, Hollow, 150 nm

WHM-23DN07 5 mL
EUR 2100

DiagNano™ S-S Monodisperse Mesoporous Silica Nanoparticles, Hollow, 350 nm

WHM-23DN14 5 mL
EUR 2100

DiagSupport™ Polystyrene Resin, 200-400 Mesh

SPS-AP23-145 100 g
EUR 660

DiagNano™ Plain Monodisperse Mesoporous Silica Nanoparticles, Hollow, 150 nm

WHM-23DN02 5 mL
EUR 1460

DiagNano™ Amine Monodisperse Mesoporous Silica Nanoparticles, Hollow, 150 nm

WHM-23DN04 5 mL
EUR 1600

DiagNano™ Thiol Monodisperse Mesoporous Silica Nanoparticles, Hollow, 150 nm

WHM-23DN08 5 mL
EUR 2100

DiagNano™ Plain Monodisperse Mesoporous Silica Nanoparticles, Hollow, 350 nm

WHM-23DN09 5 mL
EUR 1460

DiagNano™ Amine Monodisperse Mesoporous Silica Nanoparticles, Hollow, 350 nm

WHM-23DN11 5 mL
EUR 1600

DiagNano™ Thiol Monodisperse Mesoporous Silica Nanoparticles, Hollow, 350 nm

WHM-23DN15 5 mL
EUR 2100

DiagNano™ PEI Monodisperse Mesoporous Silica Nanoparticles, Dendritic, 200 nm

WHM-23DN20 5 mL
EUR 2100

Silica, fumed, hydrophobic

GK6673-1 1
EUR 136.4

Silica, fumed, hydrophobic

GK6673-250 250
EUR 54.5

DiagNano™ Amine SBA-15 Mesoporous Silica Particles, 100 μm, 40 A Pore Size

DNG-GS387 5 g
EUR 1160

DiagNano™ Amine SBA-15 Mesoporous Silica Particles, 100 μm, 60 A Pore Size

DNG-GS388 5 g
EUR 1160

DiagNano™ Amine SBA-15 Mesoporous Silica Particles, 100 μm, 80 A Pore Size

DNG-GS389 5 g
EUR 1160

DiagNano™ Amine SBA-15 Mesoporous Silica Particles, 100 μm, 100 A Pore Size

DNG-GS390 5 g
EUR 1160

DiagNano™ Amine SBA-15 Mesoporous Silica Particles, 100 μm, 120 A Pore Size

DNG-GS391 5 g
EUR 1160

DiagNano™ Amine SBA-16 Mesoporous Silica Particles, 10 μm, 60 A Pore Size

DNG-GS392 5 g
EUR 1160

DiagNano™ Thiol SBA-15 Mesoporous Silica Particles, 100 μm, 40 A Pore Size

DNG-GS393 5 g
EUR 1160

DiagNano™ Thiol SBA-15 Mesoporous Silica Particles, 100 μm, 60 A Pore Size

DNG-GS394 5 g
EUR 1160

DiagNano™ Thiol SBA-15 Mesoporous Silica Particles, 100 μm, 80 A Pore Size

DNG-GS395 5 g
EUR 1160

DiagNano™ Thiol SBA-15 Mesoporous Silica Particles, 100 μm, 100 A Pore Size

DNG-GS396 5 g
EUR 1160

DiagNano™ Thiol SBA-15 Mesoporous Silica Particles, 100 μm, 120 A Pore Size

DNG-GS397 5 g
EUR 1160

DiagNano™ Thiol SBA-16 Mesoporous Silica Particles, 10 μm, 60 A Pore Size

DNG-GS398 5 g
EUR 1160

DiagNano™ Amine MCM-41 Mesoporous Silica Particles, 100 μm, 25 A Pore Size

DNG-GS400 5 g
EUR 1160

DiagNano™ Thiol MCM-41 Mesoporous Silica Particles, 100 μm, 25 A Pore Size

DNG-GS401 5 g
EUR 1160

DiagNano™ Amine MCM-41 Mesoporous Silica Particles, 100 μm, 30 A Pore Size

DNG-GS403 5 g
EUR 1160

DiagNano™ Thiol MCM-41 Mesoporous Silica Particles, 100 μm, 30 A Pore Size

DNG-GS404 5 g
EUR 1160

DiagNano™ Amine MCM-48 Mesoporous Silica Particles, 10 μm, 25 A Pore Size

DNG-GS407 5 g
EUR 1160

DiagNano™ Thiol MCM-48 Mesoporous Silica Particles, 10 μm, 25 A Pore Size

DNG-GS408 5 g
EUR 1160

DiagNano™ Amine MCM-48 Mesoporous Silica Particles, 150 μm, 30 A Pore Size

DNG-GS410 5 g
EUR 1160

DiagNano™ Thiol MCM-48 Mesoporous Silica Particles, 150 μm, 30 A Pore Size

DNG-GS411 5 g
EUR 1160

Flash Silica 4g - PK20

CHR5156 PK20
EUR 132.3

Flash Silica 80g - PK5

CHR5196 PK5
EUR 124.2

Grids - Formvar/Carbon Coated - Copper 400 mesh

24945-100 100EA
EUR 454

Grids - Formvar/Carbon Coated - Copper 400 mesh

24945-25 25EA
EUR 132

Grids - Formvar/Carbon Coated - Copper 400 mesh

24945-50 50EA
EUR 230

Grids - Formvar/Carbon Coated - Nickel 400 mesh

24946-100 100EA
EUR 469

Grids - Formvar/Carbon Coated - Nickel 400 mesh

24946-25 25EA
EUR 163

Grids - Formvar/Carbon Coated - Nickel 400 mesh

24946-50 50EA
EUR 236

Prefilled 2.0ml tubes, 0.1mm Silica, 1.4 mm Zirconium & 4mm Silica Beads, 50pk

D1034-MX 1 PC
EUR 182.86

DiagNano™ Carboxyl Monodisperse Mesoporous Silica Nanoparticles, Hollow, 150 nm

WHM-23DN03 5 mL
EUR 1600

DiagNano™ Carboxyl Monodisperse Mesoporous Silica Nanoparticles, Hollow, 350 nm

WHM-23DN10 5 mL
EUR 1600

DiagNano™ Plain Monodisperse Mesoporous Silica Nanoparticles, Dendritic, 200 nm

WHM-23DN16 5 mL
EUR 1460

DiagNano™ Amine Monodisperse Mesoporous Silica Nanoparticles, Dendritic, 200 nm

WHM-23DN18 5 mL
EUR 1600

DiagNano™ Thiol Monodisperse Mesoporous Silica Nanoparticles, Dendritic, 200 nm

WHM-23DN22 5 mL
EUR 2100

Wang resin (200-400 mesh, 0.80-1.20 mmol/g)

4003214.0005 5 g
EUR 65.21

We find that relegation products activate platelets to a certain extent, and that degradation products generated during various periods of degradation time activate platelets to various degrees. These platelet activations occur through several mechanisms, most of which are associated with the physicochemical properties of degradation products, including ion concentration, pH, micro molecular, and molecular weight. Our findings not only provide a clearer understanding of the impact of the relegation product of the biodegradable device that contacts blood, but also provides material for filtering degradation behavior so that it can improve quality control for this device.

 

 

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