Antitumor effects and molecular mechanisms of natural product actions in ovarian cancer

Antitumor effects and molecular mechanisms of natural product actions in ovarian cancer

Ovarian cancer is a general malignancy and the second causes of the second mortality among women with genital cancer. At present, postoperative platinum drugs and paclitaxel-based chemotherapy is the treatment of gold standard for ovarian cancer. However, patients who accept these chemotherapy often experience cumulative and susceptible toxic effects on chemotherapy resistance. Therefore, it is necessary to determine the more effective treatment options that will be tolerated by the patient.

Recent studies have reported the therapeutic effects of various natural products in patients with ovarian cancer. In particular, this natural ingredient does not induce bad effects on healthy cells and networks, indicating that natural products can function as a safe alternative treatment for ovarian cancer. The antitumor effect of natural products is associated with cell proliferation oppression and metastasis, autophagy stimulation, increased chemotherapy sensitivity, and apoptosis induction.

This review focuses on the effects of antitumor from several natural products, including curcumin, resveratrol, ginsenosides, (-) – epigallocatechin-3-gallate and quercetin, which is increasingly investigated as a therapeutic option in ovarian cancer, and discusses the molecular mechanism involved in cell proliferation, apoptosis, autophagy, metastasis and sensitization.

Diseasal disinfection disinfection of precursor products from UK lowland surface water: molecular weight and bromide

The study currently compares the impact of three different unit processes, coagulation, granular activated carbon (GAC), and novels suspended ion exchange technology (six), in disinfection with the potential formation of a by-product (DBPFP) of two British lowland water sources with medium For high bromide content. Special attention is given to the influence of organic molecular weight (MW) in DBPFP and the impact of bromide concentration. While some studies have investigated the impact of the MW fraction of liquid chromatography with an analysis of organic carbon detection (LC-OCD) in the elimination of dissolved organic carbon (DOC) with a different process, no one studies the effect of the MW doc fraction of this DBP analysis.

The impact of higher bromide concentrations is to reduce the total concentration of trihalomethane mass (THM) and haloacetic (HAA), in contrast to previous reported studies. The results showed that for the source of moderate bromide concentration (135 μg / L), the potential for THM formation was reduced by 22% or 64% after coagulation or six treatments. For high bromide content sources (210 μg / L), the elimination of the potential THM formation is 47% or 69% respectively after GAC or six treatments.

The trend was the same for Haas, although with a larger difference between two processes / feedwaters with reference to the overall removal. Statistical analysis shows that organic material MW> 350 g / mol has a significant impact on DBPFP. A multiple linear regression of the MW faction against DBPFP showed a strong correlation (R2 between 0.90 and 0.93), indicating that LC-OCD analysis could only be used to predict DBP formation with reasonable accuracy, and offering potential risk assessment fast source.

Putatatat SARS-COV-2 M Pro Inhibitors from the In-House Library of Natural Products and Nature-Inspired: Virtual Screening and Molecular Docking Studies

New Coronavirus (severe acute respiratory syndrome Coronavirus 2, SARS-COV-2) has been the cause of recent global pandemic. A very contagious nature of this life-threatening virus makes it very important to find therapy to ward off diffusion. The main protease (MPRO) SARS-COV-2 is a promising target of the drug because of its very necessary role in virus replication in the host. Using a combined two-step approach from virtual screening and molecular docking techniques, we have filtered small molecular in-house collections, especially consisting of natural compounds and nature inspired. Molecules are chosen with high structural diversity to close various chemical space into an enzyme bag. Virtual screening experiments are carried out using automodock vina software docking mode.

Antitumor effects and molecular mechanisms of natural product actions in ovarian cancer

Virtual playback allows the selection of structural heterogeneous compounds that are able to interact effectively with the SARS-COV-2 MPRO enzymatic site. Compounds that show the best interaction with printed proteins by molecular docking as implemented in Autodock, while complex stability is tested by molecular dynamics. The most promising candidate reveals good ability to enter into a protein binding pocket and to reach two catalytic numbers. There is a high probability that at least one of the selected scaffes can promise for further research.

Evaluating platelet activation related to biomaterial degradation products using molecular markers

The increasing number of biodegradable medical devices can be used in the circulatory system. The effects of relegation products released from this medical device on blood may be gradual and cumulative. When they reach a critical level, they can cause thrombosis and other complications. For this reason, it is important to evaluate blood compatibility of relegation products for quality control and development of this device. In this study, we evaluated the relegation products of four biodegradable materials (collagen, polylactic acid, calcium phosphate ceramics, and magnesium) using molecular markers of thrombosis activation associated with thrombosis.

Silica gel 100 - 200 mesh

GRM7479-25KG 1 unit
EUR 515.93
Description: Silica gel 100 - 200 mesh

Silica gel 100 - 200 mesh

GRM7479-500G 1 unit
EUR 11.47
Description: Silica gel 100 - 200 mesh

Silica gel 60 - 120 mesh

GRM7477-25KG 1 unit
EUR 420.18
Description: Silica gel 60 - 120 mesh

Silica gel 60 - 120 mesh

GRM7477-500G 1 unit
EUR 9.34
Description: Silica gel 60 - 120 mesh

Silica gel 60 - 200 mesh

GRM7478-500G 1 unit
EUR 9.45
Description: Silica gel 60 - 200 mesh

Silica Gel Grade 03 8 Mesh

S02570 1KG
EUR 85.3
Description: CAS N° 7631-86-9

Silica Gel Grade 408 12-24 Mesh

S02577 500G
EUR 219.6
Description: CAS N° 7631-86-9

Silica Gel Grade 40 -6+12 Mesh (1680-3350 microns)

S02572 250G
EUR 119.2
Description: CAS N° 7631-86-9

Silica Gel Blue (Self Indicating) (Coarse), 5-8 mesh

85148 500 Gms
EUR 3.63
Description: Part A

Silica Gel

30615-85 500G
EUR 19.6

Silica Gel

30619-45 500G
EUR 19.6

Silica Gel

17091-55 500G
EUR 12.25

Silica Gel

17092-45 500G
EUR 19.6

Silica gel

GRM151-1KG 1 unit
EUR 11.28
Description: Silica gel

Silica gel

GRM151-500G 1 unit
EUR 6.93
Description: Silica gel

Silica gel

GRM151-5KG 1 unit
EUR 50.46
Description: Silica gel

Silica Gel G for TLC, 325mesh, w/ CaSO4

51849 500 Gms
EUR 3.69
Description: Part A

Silica Gel H for TLC, 325mesh, w/o CaSO4

52797 500 Gms
EUR 3.69
Description: Part A

Silica Gel 60

30721-01 1KG
EUR 81.9

Silica Gel 60

30721-14 5KG
EUR 298.9

Silica Gel 60

30721-85 500G
EUR 49

Silica Gel 60

30724-55 500G
EUR 27.3

Silica Gel 60

30724-71 1KG
EUR 49.7

Silica Gel 60

30724-84 5KG
EUR 205.1

Silica gel H

GRM602-500G 1 unit
EUR 10.29
Description: Silica gel H

Silicon carbide 400 mesh

GRM7488-1KG 1 unit
EUR 70.04
Description: Silicon carbide 400 mesh

Silicon carbide 400 mesh

GRM7488-250G 1 unit
EUR 18.94
Description: Silicon carbide 400 mesh

Silica gel GF 254

GRM367-500G 1 unit
EUR 64.32
Description: Silica gel GF 254

Silica Gel 120, spherical

30734-41 1KG
EUR 56.7

Silica Gel 60, spherical

30731-42 25KG
EUR 957.6

Silica Gel 60, spherical

30731-71 1KG
EUR 51.8

Drying Reagent, Silica Gel

DSG110 1Kg
EUR 91.32

Silica Gel GF254 for TLC, 325mesh, w/ Fluorescent Indicator w/ CaSO4

38062 500 Gms
EUR 26.68
Description: Part A

Silica gel G For TLC

GRM7480-500G 1 unit
EUR 10.87
Description: Silica gel G For TLC

Silica Gel with 3% AgNO3

S450270 10g
EUR 800

Silica Gel HF254 for TLC, 325mesh, w/ Fluorescent Indicator w/o CaSO4

29774 500 Gms
EUR 26.68
Description: Part A

Silica gel HF 254 For TLC

GRM7482-500G 1 unit
EUR 70.56
Description: Silica gel HF 254 For TLC

Silica Gel Fumed 200 (Hydrophilic)

84210 100 Gms
EUR 3.22
Description: Part A

Silica Gel 60, spherical, neutral

30511-06 5KG
EUR 343

Silica Gel 60, spherical, neutral

30511-22 25KG
EUR 1540

Silica Gel 60, spherical, neutral

30511-35 500G
EUR 57.4

Silica Gel 60, spherical, neutral

30511-51 1KG
EUR 98

Silica Gel 60, spherical, neutral

30511-64 100G
EUR 21

Silica Gel 60, spherical, neutral

30518-65 500G
EUR 42

Silica Gel 60, spherical, neutral

30518-81 1KG
EUR 66.5

Silica Gel 60, spherical, neutral

30518-94 100G
EUR 17.5

Silica Gel, 40-63 Micron Particles

S450200 1kg
EUR 787
Description: 112926-00-8

Silica Gel, 35-70 Micron Particles

S450400 2.5kg
EUR 667
Description: 112926-00-6

Silica gel orange 360 g - EACH

DD490938 EACH
EUR 87.75

Silica Gel Large Pore 70 microns

S02580 100G
EUR 102.24
Description: CAS N° 1343-98-2

Silica Gel In Bag, 5G, 100/Pk

DSG111 1PK, 100UNIT
EUR 73.57

Silica Gel Grade 12 High Purity Chromatographic Gel 28-20

S02571 1KG
EUR 140.95
Description: CAS N° 112945-52-5

5g Silica Gel Sachets In Tyvek - PK1000

X17976 PK1000
EUR 130.72

Silica Gel Orange (Self Indicating), 2-5mm

71548 500 Gms
EUR 4.11
Description: Part A

3-Aminopropyl-funtionalized Silica Gel (40-63 μm)

A450215 1g
EUR 132

Silica Gel Grade 923 High Purity Chromatographic_x000D_

S02578 100G
EUR 239.23
Description: CAS N° 7631-86-9

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254 500g
EUR 159.23

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254-1 1
EUR 47.4

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254-1KG 1 kg
EUR 93.6

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254-5 5
EUR 174

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254-500 500
EUR 27.8

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254-500G 500 g
EUR 69.6

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254-5KG 5 kg
EUR 246

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287 500g
EUR 159.23

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287-1 1
EUR 47.4

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287-1KG 1 kg
EUR 93.6

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287-5 5
EUR 174

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287-500 500
EUR 27.8

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287-500G 500 g
EUR 69.6

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287-5KG 5 kg
EUR 246

C18 Silica Gel (>10% C-18; Capped With TMS)

S452500 50g
EUR 265

Silica gel, pore size 60A, particle size 40-63 micron

GX9977 1kg
EUR 49.79

Silica gel, pore size 60A, particle size 40-63 micron

GX9977-1 1
EUR 54.4

Silica gel, pore size 60A, particle size 40-63 micron

GX9977-1KG 1 kg
EUR 102

Silica Gel, self-indicating, blue to pink, 2 - 5 mm beads

GE5162 500g
EUR 195.68

Silica Gel, self-indicating, blue to pink, 2 - 5 mm beads

GE5162-1 1
EUR 58.4

Silica Gel, self-indicating, blue to pink, 2 - 5 mm beads

GE5162-1KG 1 kg
EUR 106.8

Silica Gel, self-indicating, blue to pink, 2 - 5 mm beads

GE5162-5 5
EUR 213.7

Silica Gel, self-indicating, blue to pink, 2 - 5 mm beads

GE5162-500 500
EUR 33.1

Silica Gel, self-indicating, blue to pink, 2 - 5 mm beads

GE5162-500G 500 g
EUR 76.8

Silica Gel, self-indicating, blue to pink, 2 - 5 mm beads

GE5162-5KG 5 kg
EUR 294

Silica Gel, self-indicating, orange to green, 2 - 5 mm beads

GE5612 500g
EUR 208.67

DiagNano™ Silica Particles, 400 nm

DNG-B008 10 mL
EUR 560

Silicon carbide 220 mesh

GRM7487-1KG 1 unit
EUR 84.04
Description: Silicon carbide 220 mesh

Silicon carbide 220 mesh

GRM7487-250G 1 unit
EUR 24.12
Description: Silicon carbide 220 mesh

Silicon powder 99.999% -325 Mesh

S02610 25G
EUR 352.06
Description: CAS N° 7440-21-3

Silicon carbide 99% -100 Mesh

S02620 500G
EUR 180
Description: CAS N° 409-21-2

Silicon dioxide 99.5% -325 MESH

S02645 250G
EUR 137.4
Description: CAS N° 7631-86-9

Silica Gel, self-indicating, orange to colourless, 4 - 8 mm beads, cobalt free

GE9411 500g
EUR 55.02

Silica Gel, self-indicating, orange to colourless, 4 - 8 mm beads, cobalt free

GE9411-1 1
EUR 60.1

Silica Gel, self-indicating, orange to colourless, 4 - 8 mm beads, cobalt free

GE9411-1KG 1 kg
EUR 109.2

Silica Gel, self-indicating, orange to colourless, 4 - 8 mm beads, cobalt free

GE9411-500 500
EUR 35.5

Silica Gel, self-indicating, orange to colourless, 4 - 8 mm beads, cobalt free

GE9411-500G 500 g
EUR 79.2

Silicon(IV) oxide, 99.99%, -100 mesh

GX8518 50g
EUR 406.18

Silicon(IV) oxide, 99.99%, -100 mesh

GX8518-250 250
EUR 356.8

Silicon(IV) oxide, 99.99%, -100 mesh

GX8518-50 50
EUR 140.2

Foil pouch and silica gel pack for storage of microtitre (ELISA) plates (10 pcs)

100191 10 pcs
EUR 22
Description: Foil pouch and silica gel pack for storage of microtitre (ELISA) plates (10 pcs)

Silicon Metal powder, 98.5%, -200 mesh

73081 100 Gms
EUR 2.4
Description: Part B

Silver Metal powder, 99.9%, -400 mesh

32422 10 Gms
EUR 24.75
Description: Part B

Silicon nitride -325 or -2500 mesh sizes

S02660 10G
EUR 139.5
Description: CAS N° 12033-89-5

MagIso™ cfDNA Silica Magnetic Particles, 400 nm

WHK-C031 10 ml
EUR 500

Silicon Metal powder, 98.5%, -4 mesh

79427 500 Gms
EUR 9.75
Description: Part B

Silicon Powder -100, +325 mesh, amorphous, 99.999%

GX3061 50g
EUR 973.41

Silicon Powder -100, +325 mesh, amorphous, 99.999%

GX3061-250 250
EUR 840.8

Silicon Powder -100, +325 mesh, amorphous, 99.999%

GX3061-50 50
EUR 236.2

DiagNano™ Plain Silica Particles, Nonporous, 400 nm, Powder

DNG-GS355 5 g
EUR 928

Silica

si300 2 ML
EUR 367.5

Zeolite - Mesoporous Silica Molecular Sieve Kit-6

65276 1 Gms
EUR 124.34
Description: Part C

Zeolite - Mesoporous Silica Nanopowder (SBA-15 Type)

83881 250 Mg
EUR 31.09
Description: Part C

Zeolite - Mesoporous Silica Nanopowder (SBA-15 Type)

83881-1 1 Gms
EUR 93.55
Description: Part C

Bromoacetyl resin (200-400 mesh)

4029092.0005 5 g
EUR 317.94

Bromoacetyl resin (200-400 mesh)

D-2555.0001 1.0g
EUR 166.8

Bromoacetyl resin (200-400 mesh)

D-2555.0005 5.0g
EUR 529.2

DiagNano™ Li Ion Silica Particles, Nonporous, 400 nm, Powder

DNG-GS356 5 g
EUR 928

DiagNano™ PEI Mesoporous Silica Nanoparticles, 50 nm

WHM-23DN27 5 mL
EUR 1280

DiagNano™ PEI Mesoporous Silica Nanoparticles, 100 nm

WHM-23DN45 5 mL
EUR 1280

DiagNano™ Carboxyl Mesoporous Silica Particles, 3 μm

DNG-C046 10 mL
EUR 1020

DiagNano™ Plain Mesoporous Silica Nanoparticles, 50 nm

WHM-23DN23 5 mL
EUR 928

DiagNano™ Amine Mesoporous Silica Nanoparticles, 50 nm

WHM-23DN25 5 mL
EUR 976

DiagNano™ Thiol Mesoporous Silica Nanoparticles, 50 nm

WHM-23DN29 5 mL
EUR 1280

DiagNano™ Plain Mesoporous Silica Nanoparticles, 100 nm

WHM-23DN41 5 mL
EUR 928

DiagNano™ Amine Mesoporous Silica Nanoparticles, 100 nm

WHM-23DN43 5 mL
EUR 976

DiagNano™ Thiol Mesoporous Silica Nanoparticles, 100 nm

WHM-23DN47 5 mL
EUR 1280

DiagNano™ S-S Mesoporous Silica Nanoparticles, 50 nm

WHM-23DN28 5 mL
EUR 1280

DiagNano™ S-S Mesoporous Silica Nanoparticles, 100 nm

WHM-23DN46 5 mL
EUR 1280

DiagNano™ Carboxyl Mesoporous Silica Nanoparticles, 50 nm

WHM-23DN24 5 mL
EUR 976

DiagNano™ Carboxyl Mesoporous Silica Nanoparticles, 100 nm

WHM-23DN42 5 mL
EUR 976

Dowex® 50WX2, 200-400 mesh

RM2810-250G 1 unit
EUR 273.58
Description: Dowex® 50WX2, 200-400 mesh

Dowex® 50WX8, 200-400 mesh

RM2815-250G 1 unit
EUR 424.54
Description: Dowex® 50WX8, 200-400 mesh

Zeolite - Mesoporous Silica Nanopowder (3D-Cubic MCM-48 Type)

63876 250 Mg
EUR 143.88
Description: Part C

Zeolite - Mesoporous Silica Nanopowder (3D-Cubic MCM-48 Type)

63876-1 500 Mg
EUR 210.99
Description: Part C

Amorphous silica

HY-154739A Get quote Ask for price
Description: Amorphous silica can be used as an excipient, such as viscosifier, suspending agent, tablet disintegrating agent, adsorbent dispersing agent as liquid in powders. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

DiagNano™ PEG Carboxyl Mesoporous Silica Nanoparticles, 50 nm

WHM-23DN26 5 mL
EUR 1280

DiagNano™ PEG Carboxyl Mesoporous Silica Nanoparticles, 100 nm

WHM-23DN44 5 mL
EUR 1280

Grids - Carbon Coated - Copper 400 mesh

24948-100 100EA
EUR 633.96

Grids - Carbon Coated - Copper 400 mesh

24948-25 25EA
EUR 171.72

Grids - Carbon Coated - Copper 400 mesh

24948-50 50EA
EUR 317.52

DiagNano™ Li Ion Silica Particles, Nonporous, 400 nm, Ethanol Dispersion

DNG-GS370 2 ml
EUR 848

Zeolite - Mesoporous Silica Nanopowder (1D-Hexagonal SBA-41 Type)

97621 250 Mg
EUR 143.88
Description: Part C

Zeolite - Mesoporous Silica Nanopowder (1D-Hexagonal SBA-41 Type)

97621-1 500 Mg
EUR 210.99
Description: Part C

Flash Silica 120g - PK5

CHR5204 PK5
EUR 152.55

DiagNano™ Mesoporous Silica Coated Upconverting Nanoparticles, 365 nm

DNL-S006 10 mg
EUR 1424

DiagNano™ Mesoporous Silica Coated Upconverting Nanoparticles, 475 nm

DNL-S007 10 mg
EUR 1424

DiagNano™ Mesoporous Silica Coated Upconverting Nanoparticles, 545 nm

DNL-S008 10 mg
EUR 1424

DiagNano™ Mesoporous Silica Coated Upconverting Nanoparticles, 660 nm

DNL-S009 10 mg
EUR 1424

DiagNano™ Mesoporous Silica Coated Upconverting Nanoparticles, 804 nm

DNL-S010 10 mg
EUR 1424

Wang Resin (200-400 mesh) 1% DVB

MBS406673-25g 25g
EUR 340

Wang Resin (200-400 mesh) 1% DVB

MBS406673-5g 5g
EUR 165

Wang Resin (200-400 mesh) 1% DVB

MBS406673-5x25g 5x25g
EUR 1470

Wang Resin (200-400 mesh) 1% DVB

MBS406673-5x5g 5x5g
EUR 685

Flash Silica 330g - EACH

CHR5208 EACH
EUR 124.2

DiagNano™ SBA-15 Mesoporous Silica Particles, 100 μm, 40 A Pore Size

DNG-GS379 5 g
EUR 768

DiagNano™ SBA-15 Mesoporous Silica Particles, 100 μm, 60 A Pore Size

DNG-GS380 5 g
EUR 768

DiagNano™ SBA-15 Mesoporous Silica Particles, 100 μm, 80 A Pore Size

DNG-GS381 5 g
EUR 768

DiagNano™ SBA-15 Mesoporous Silica Particles, 100 μm, 100 A Pore Size

DNG-GS382 5 g
EUR 768

DiagNano™ SBA-15 Mesoporous Silica Particles, 100 μm, 120 A Pore Size

DNG-GS383 5 g
EUR 768

DiagNano™ SBA-16 Mesoporous Silica Particles, 10 μm, 60 A Pore Size

DNG-GS384 5 g
EUR 768

DiagNano™ MCM-41 Mesoporous Silica Particles, 100 μm, 25 A Pore Size

DNG-GS399 5 g
EUR 768

DiagNano™ MCM-41 Mesoporous Silica Particles, 100 μm, 30 A Pore Size

DNG-GS402 5 g
EUR 768

DiagNano™ MCM-48 Mesoporous Silica Particles, 10 μm, 25 A Pore Size

DNG-GS406 5 g
EUR 768

DiagNano™ MCM-48 Mesoporous Silica Particles, 150 μm, 30 A Pore Size

DNG-GS409 5 g
EUR 768

DiagNano™ PEI Monodisperse Mesoporous Silica Nanoparticles, Hollow, 150 nm

WHM-23DN06 5 mL
EUR 1680

DiagNano™ PEI Monodisperse Mesoporous Silica Nanoparticles, Hollow, 350 nm

WHM-23DN13 5 mL
EUR 1680

DiagSupport™ Polystyrene Resin, 200-400 Mesh

SPS-AP23-145 100 g
EUR 528

Silica Microspheres, 0.50µm

24323-15 15ml
EUR 588.6

Silica Microspheres, 0.70µm

24324-15 15ml
EUR 708.48

Silica Microspheres, 3.0µm

24330-15 15ml
EUR 990.36

Silica Microspheres, 4.0µm

24331-15 15ml
EUR 990.36

Silica Microspheres, 0.15µm

24320-15 15ml
EUR 588.6

Silica Microspheres, 0.30µm

24321-15 15ml
EUR 588.6

Silica Microspheres, 0.40µm

24322-15 15ml
EUR 588.6

Silica Microspheres, 0.90µm

24325-15 15ml
EUR 708.48

Silica Microspheres, 1.0µm

24326-15 15ml
EUR 708.48

Silica Microspheres, 1.5µm

24327-15 15ml
EUR 841.32

Silica Microspheres, 2.0µm

24328-15 15ml
EUR 841.32

Silica Microspheres, 2.5µm

24329-15 15ml
EUR 841.32

Silica Microspheres, 5.0µm

24332-15 15ml
EUR 990.36

Prefilled 2.0mL tubes 0.1mm Silica 1.4mm Zr 4mm Silica Bead 50pk - PK50

HOM3038 PK50
EUR 265.95

Silica, fumed, hydrophobic

GK6673 250g
EUR 124.87

Silica, fumed, hydrophobic

GK6673-1 1
EUR 136.4

Silica, fumed, hydrophobic

GK6673-250 250
EUR 54.5

DiagNano™ S-S Monodisperse Mesoporous Silica Nanoparticles, Hollow, 150 nm

WHM-23DN07 5 mL
EUR 1680

DiagNano™ S-S Monodisperse Mesoporous Silica Nanoparticles, Hollow, 350 nm

WHM-23DN14 5 mL
EUR 1680

DiagNano™ Plain Monodisperse Mesoporous Silica Nanoparticles, Hollow, 150 nm

WHM-23DN02 5 mL
EUR 1168

DiagNano™ Amine Monodisperse Mesoporous Silica Nanoparticles, Hollow, 150 nm

WHM-23DN04 5 mL
EUR 1280

DiagNano™ Thiol Monodisperse Mesoporous Silica Nanoparticles, Hollow, 150 nm

WHM-23DN08 5 mL
EUR 1680

DiagNano™ Plain Monodisperse Mesoporous Silica Nanoparticles, Hollow, 350 nm

WHM-23DN09 5 mL
EUR 1168

DiagNano™ Amine Monodisperse Mesoporous Silica Nanoparticles, Hollow, 350 nm

WHM-23DN11 5 mL
EUR 1280

We find that relegation products activate platelets to a certain extent, and that degradation products generated during various periods of degradation time activate platelets to various degrees. These platelet activations occur through several mechanisms, most of which are associated with the physicochemical properties of degradation products, including ion concentration, pH, micro molecular, and molecular weight. Our findings not only provide a clearer understanding of the impact of the relegation product of the biodegradable device that contacts blood, but also provides material for filtering degradation behavior so that it can improve quality control for this device.

 

 

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