Activation of genomics is directed at the natural program pathways Cryptic Decipshers code for biosynthesis and molecular functions

Activation of genomics is directed at the natural program pathways Cryptic Decipshers code for biosynthesis and molecular functions

Natural products, which can be isolated from living organisms around the world, have played an important role in drug discovery since ancient times. However, it has become more challenging to identify novel molecules structurally with promising biological activities for pharmaceutical development, especially because the methodology is limited to their acquisition. In this review, we summarize our research recently that activates the potential biosynthesis of fungal filaments by genetic engineering to utilize the flow of metabolism for natural product production that has never happened before.

The recent revolution in the genome sequencing technology allows accumulated a large amount of information about biosynthetic genes, molecular construction blueprint. Utilizing the specified heterologist expression system, activation of specific path transcription factors coupled with the knockout system strategy, and manipulating the global regulatory gene, biosintetic genes are exploited to activate the biosynthetic pathways and describe encoded enzyme functions. We show that this methodology is useful for acquiring fungal assets for drug discovery. These studies also allow the investigation of the molecular function of natural products in the development of fungi.

Virtual screening and molecular simulation study database natural products for lead identification novel novel coronavirus protease inhibitors

3CL LIKE PROTEASE (3CLPRO or MPRO) is one of the main proteases of 2019-Ncov. 3CLPRO is a nontructural protein of SARS-COV and has an important role in viral replication and transcription, thus, can be a potential target for the development of anti-SARS drugs. This study employs a ligand and structural-based approach to identify the effective inhibitor of Protease 2019-NCOV. E-pharmacophore developed from a virtual hit produced by 3CLPro-1, which is worn through the possibility of drugs and filter pain to eliminate disturbing compounds.

A further comprehensive docking study, free energy calculations and admation studies produce two lead virtual-molport-000-410-348 and molport-002-530-156. MOLPORT-000-410-348 and MOLPORT-002-530-156 compounds display good docking scores from -12.09 and -13.38 kcal / mol and free binder energy -63.34 ± 2.03 and -61.52 ± 2.24 kcal / mole. Compounds also showcase Predike Profile predictions and subject to Dynamic Molecular Studies (MD). MD simulation produces a stable complex of these ligands with 3CLPRO proteins and RMSD ligands within acceptable limits. Communicated by Ramaswamy H. Sarma.

Relationship between activities, molecular docking, and molecular dynamic studies from expending from marine natural products with anti-HIV activity

HIV-1 infection is a global epidemic whose treatment is limited to the majority by viral resistance and side effects. Natural products from algae have been studied for years, including antivirus, becoming an alternative to the design of anti-HIV drugs. Because natural product insulation can be in the form of obstacles, molecular modeling is an important tool for studying these compounds. Here, relationships of activities, molecular docking, and molecular dynamic studies are carried out to direct the study of ten natural marine products with anti-HIV activity.

Activation of genomics is directed at the natural program pathways Cryptic Decipshers code for biosynthesis and molecular functions

In the relationship between activities, the descriptor is identified associating the activity of anti-HIV five by passing with possible actions on the Alostalister transcriptase site back. Diarpene was evaluated by molecular docking, and was identified that only dolabelladirioletririol was interacting on the alosteric site. Molecular dynamics suggest that dolabelladienetririol can disrupt the RNA virus that binds for HIV-1 RT by inducing changes in enzyme conformation. Also, in Silico’s simulation, predict that the dolabelladiriol presents high

Molecular genome features related to in vitro responses from NCI-60 cancer cell line panels to natural products

Natural products remain a significant source of anti-cancer chemotherapy. Searching for drugs targeted for cancer treatment includes consideration of natural products that can provide new opportunities for anti-tumor cytotoxicity as a single agent or in combination therapy. We examine the association of molecular genome features in the NCI-60 cancer cell line panel well with in vitro responses to treatment with 1,302 small molecules that include natural products, semi-synthetic natural products, and synthetic compounds based on natural products Farmacophore from the therapy program Progression of national national cancer institute database. These compounds are obtained from various plant, sea and microbial species.

Molecular information used for analysis including expression size for 23,059 annotation transcripts, LNCRNAS, and MIRNAS, and data on a single nucleotide variant that changes protein in 211 genes related to cancer. We found the associations of various genes including SLFN11, CYP2J2, EFX1, GPC1, ELF3, and MGMT involved in improving DNA damage, family members of notch, ABC and SLC Transporter, and both mutations in Tyrosine and Braf V600e kinases with NCI response with NCI -60 for the specific category of natural products. Hierarchical clustering identifies a group of natural products that correlate with certain action mechanisms.

In particular, some natural product clusters are associated with the expression of the SLFN11 gene, indicating that the potential actions of this compound can involve damage to DNA. The association between gene expression or changes in genome genomes is relevant functionally with cancer cell responses to natural products providing new information about the potential mechanism of action from a group of potential biological compounds. This information will help the discovery of drugs in the future and in the design of new cancer chemotherapy agents targeted.

A new approach based on the polyethylene form of multi-ultra high molecular weight glued to make bone replacement products

Three types of glue based on Tiol-ENE reactions, polyvinyl alcohol (PVA) / cellulose, and phenol formaldehyde is prepared and applied to the weight of the modified molecular weight polyethylene weight (UHMWPE) grafted by cellulose. Compared to unmodified UHMWPE samples, the T-Peel test in the modified UHMWPE film and grafted shows an increase in the value of skin strength for glue based on the reaction of Tiol-ENE, PVA / cellulose, and formaldehyde phenol by 40, 29, and 41 times, each each. The maximum peeled strength value of 0.62 kg / cm is obtained so that glue based on formaldehyde phenol.

 

SC-PEG-SC,400

33-HO023023-400
  • EUR 200.40
  • EUR 478.80
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SH-PEG-NH-Methoxyphenone,400

33-HE003071-400
  • EUR 622.80
  • EUR 1658.40
  • 100mg
  • 500mg
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

DSPE-PEG-NH2

33-LP096005-400
  • EUR 829.20
  • EUR 2367.60
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

HO-PEG-NH2,400

33-HE002005-400
  • EUR 504.00
  • EUR 1392.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SH-PEG-NH2,400

33-HE003005-400
  • EUR 1909.20
  • EUR 681.60
  • 5g
  • g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

MAL-PEG-NH2,400

33-HE022005-400
  • EUR 622.80
  • EUR 1747.20
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

NH2-PEG-NH2,400

33-HO005005-400
  • EUR 282.00
  • EUR 726.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Drying Reagent, Silica Gel

DSG110 1Kg
EUR 91.32

Silica gel orange 360 g

DD490938 EACH
EUR 54.49

DiagNano Silica Particles, 400 nm

DNG-B008 10 mL
EUR 670.8

Bromoacetyl resin (200-400 mesh)

D-2555.0001 1.0g
EUR 166.8

Bromoacetyl resin (200-400 mesh)

D-2555.0005 5.0g
EUR 529.2

5g Silica Gel Sachets In Tyvek

X17976 PK1000
EUR 92.34

DiagNano Silica Particles, 700 nm

DNG-B011 10 mL
EUR 682.8

Silica Gel In Bag, 5G, 100/Pk

DSG111 1PK, 100UNIT
EUR 73.57

FA-PEG-NHS,400

HE057023-400-100mg 100mg
EUR 452.4
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

OH-PEG-OH,400

HO002002-400-10g 10g
EUR 367.2
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

FITC-PEG-Alkyne,400

FL044007-400-100mg 100mg
EUR 681.6
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

PCS-700-040 Growth Kit

PCS-700 RT 500 mL Bottle
EUR 265.2

Indexed MicroMesh; box of 20 with 400 micron Diameter and 25 micron mesh Opening

M3-L18SP-400/25-IN1 20 MOUNTS
EUR 112
Description: Indexed MicroMesh; box of 20 with 400 micron Diameter and 25 micron mesh Opening

Gellan Gum, Pure, Plant Culture Grade, ≥ 80% transmittance,Gel strength 400-700 g/cm2

G2007-050 500g
EUR 360

Gellan Gum, Pure, Plant Culture Grade, ≥ 80% transmittance,Gel strength 400-700 g/cm2

G2007-100 1Kg
EUR 562.8

Gellan Gum, Pure, Plant Culture Grade, ≥ 80% transmittance,Gel strength 400-700 g/cm2

G2007-500 5Kg
EUR 2101.2

Turbidity Std Ratio 400 NTU

CRSR-400-100 100ML
EUR 191.52

Turbidity Std Ratio 400 NTU

CRSR-400-500 500ML
EUR 399

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1

B-M3-400/25IN1-B1 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1A

B-M3-400/25IN1-B1A 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1A

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3

B-M3-400/25IN1-B3 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3S

B-M3-400/25IN1-B3S 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3S

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B5

B-M3-400/25IN1-B5 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B5

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1

B-M3-400/25IN2-B1 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1A

B-M3-400/25IN2-B1A 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1A

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3

B-M3-400/25IN2-B3 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3S

B-M3-400/25IN2-B3S 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3S

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B5

B-M3-400/25IN2-B5 20 MOUNT/BASE ASSEMBLIES
EUR 249
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B5

Indexed MicroMesh; box of 20 with 400 micron Diameter and 25 micron mesh Opening, Square Openings

M3-L18SP-400/25-IN2 20 MOUNTS
EUR 112
Description: Indexed MicroMesh; box of 20 with 400 micron Diameter and 25 micron mesh Opening, Square Openings

Turbidity Std Non Ratio 400 NTU

CRS-400-100 100ML
EUR 191.52

Turbidity Std Non Ratio 400 NTU

CRS-400-500 500ML
EUR 399

Iodopolystyrene resin (200-400 mesh, > 1 mmol/g)

D-2260.0001 1.0g
EUR 211.2

Iodopolystyrene resin (200-400 mesh, > 1 mmol/g)

D-2260.0005 5.0g
EUR 733.2

4-(Fmoc-hydrazino)-benzoylaminomethyl resin (200-400 mesh)

D-2560.0001 1.0g
EUR 240

4-(Fmoc-hydrazino)-benzoylaminomethyl resin (200-400 mesh)

D-2560.0005 5.0g
EUR 835.2

4-Formyl-phenyloxymethyl polystyrene resin (200-400 mesh)

D-2575.0001 1.0g
EUR 166.8

4-Formyl-phenyloxymethyl polystyrene resin (200-400 mesh)

D-2575.0005 5.0g
EUR 572.4

Quantifoil R1.2/1.3 400 Mesh, Copper (100/pk)

M-CEM-Q4100CR1.3 100 GRIDS
EUR 700
Description: Quantifoil R1.2/1.3 400 Mesh, Copper (100/pk)

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254-1KG 1 kg
EUR 93.6

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254-500G 500 g
EUR 69.6

Silica Gel, pore size ~25A, 2 - 5 mm beads

GX6254-5KG 5 kg
EUR 246

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287-1KG 1 kg
EUR 93.6

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287-500G 500 g
EUR 69.6

Silica Gel, pore size ~25A, 1 - 3 mm beads

GX9287-5KG 5 kg
EUR 246

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1-R

B-M3-400/25IN1-B1-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1A-R

B-M3-400/25IN1-B1A-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B1A-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3-R

B-M3-400/25IN1-B3-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3S-R

B-M3-400/25IN1-B3S-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B3S-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B5-R

B-M3-400/25IN1-B5-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN1 (in um) Base Style B5-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1-R

B-M3-400/25IN2-B1-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1A-R

B-M3-400/25IN2-B1A-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B1A-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3-R

B-M3-400/25IN2-B3-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3S-R

B-M3-400/25IN2-B3S-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B3S-R

MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B5-R

B-M3-400/25IN2-B5-R 20 MOUNT/BASE ASSEMBLIES
EUR 339
Description: MicroMesh Epoxied Assembly Head Diameter and Mesh Opening 400/25IN2 (in um) Base Style B5-R

TIPS GEL-G,10UL,FT,NS,RK,200/400

4815 200/pk
EUR 166.8
Description: Non Filter Tips; Costar Specialty Tips

Sulfur 400 ug/g (400 PPM) for AA and ICP 100 grams in no.2 Diesel Fuel

SDFS-400-Y 100ML
EUR 102.6

Anti-Alexa Fluor 647 Antibody | M647-65A-400

M647-65A-400 1.0 mg
EUR 379
Description:

Anti-Alexa Fluor 647 Antibody | M647-65A-400 | Immunology Consultants Laboratory

Host: Mouse

Format: Unconjugated AP

Product Type: Primary Antibody

Antibody Clonality: Monoclonal

Silica gel, pore size 60A, particle size 40-63 micron

GX9977-1KG 1 kg
EUR 102

Aminomethyl resin (200-400 mesh, 0.80-1.20 mmol/g)

D-1005.0005 5.0g
EUR 138
Description: CAS# [78578-28-6]

Aminomethyl resin (200-400 mesh, 0.80-1.20 mmol/g)

D-1005.0025 25.0g
EUR 370.8
Description: CAS# [78578-28-6]

Aminomethyl resin (200-400 mesh, 0.80-1.20 mmol/g)

D-1005.0100 100.0g
EUR 1009.2
Description: CAS# [78578-28-6]

Hydroxymethyl resin (200-400 mesh, 0.9-1.4 mmol/g)

D-1160.0025 25.0g
EUR 340.8
Description: CAS# [66072-40-0]

Hydroxymethyl resin (200-400 mesh, 0.9-1.4 mmol/g)

D-1160.0100 100.0g
EUR 950.4
Description: CAS# [66072-40-0]

Merrifield resin (200-400 mesh, 0.80-1.40 mmol/g)

D-1245.0025 25.0g
EUR 181.2
Description: CAS# [55844-94-5]

Merrifield resin (200-400 mesh, 0.80-1.40 mmol/g)

D-1245.0100 100.0g
EUR 471.6
Description: CAS# [55844-94-5]

Wang resin (200-400 mesh, 0.80-1.20 mmol/g)

D-1250.0005 5.0g
EUR 138

Wang resin (200-400 mesh, 0.80-1.20 mmol/g)

D-1250.0025 25.0g
EUR 385.2

Wang resin (200-400 mesh, 0.80-1.20 mmol/g)

D-1250.0100 100.0g
EUR 1096.8

SASRIN resin (200-400 mesh, 0.80-1.20 mmol/g)

D-1295.0001 1.0g
EUR 194.4
Description: CAS# [124760-64-1]

SASRIN resin (200-400 mesh, 0.80-1.20 mmol/g)

D-1295.0005 5.0g
EUR 646.8
Description: CAS# [124760-64-1]

SASRIN resin (200-400 mesh, 0.80-1.20 mmol/g)

D-1295.0025 25.0g
EUR 2473.2
Description: CAS# [124760-64-1]

PAL resin (200-400 mesh, 0.2-0.5 mmol/g)

D-2125.0001 1.0g
EUR 270

PAL resin (200-400 mesh, 0.2-0.5 mmol/g)

D-2125.0005 5.0g
EUR 963.6

Isocyanomethyl resin (200-400 mesh, 0.7-1.0 mmol/g)

D-2225.0001 1.0g
EUR 240

Isocyanomethyl resin (200-400 mesh, 0.7-1.0 mmol/g)

D-2225.0005 5.0g
EUR 835.2

Diphenyldiazomethane resin (200-400 mesh, 0.7-1.3 mmol/g)

D-2230.0001 1.0g
EUR 340.8

Diphenyldiazomethane resin (200-400 mesh, 0.7-1.3 mmol/g)

D-2230.0005 5.0g
EUR 1240.8

Thiomethyl resin (200-400 mesh, 0.9-1.2 mmol/g)

D-2235.0001 1.0g
EUR 240

Thiomethyl resin (200-400 mesh, 0.9-1.2 mmol/g)

D-2235.0005 5.0g
EUR 835.2

Carbon Film of Copper Grid, 400 mesh, 50/pk

M-CEM-CF400-Cu 50 GRIDS
EUR 111
Description: Carbon Film of Copper Grid, 400 mesh, 50/pk

Formvar Film of Copper Grid, 400 mesh, 50/pk

M-CEM-FF400-Cu 50 GRIDS
EUR 67
Description: Formvar Film of Copper Grid, 400 mesh, 50/pk

Quantifoil R 3/3; Copper 400 Mesh 100/pk

M-CEM-Q3100CR3 100 GRIDS
EUR 718
Description: Quantifoil R 3/3; Copper 400 Mesh 100/pk

Quantifoil R 1/2 ; Gold 400 Mesh 100/pk

M-CEM-Q4100AR-12 100 GRIDS
EUR 925
Description: Quantifoil R 1/2 ; Gold 400 Mesh 100/pk

Quantifoil R 2/1 ; Gold 400 Mesh 100/pk

M-CEM-Q4100AR1 100 GRIDS
EUR 925
Description: Quantifoil R 2/1 ; Gold 400 Mesh 100/pk

Quantifoil R 1.2/1.3, Gold 400 mesh 100/pk

M-CEM-Q4100AR1.3 100 GRIDS
EUR 820
Description: Quantifoil R 1.2/1.3, Gold 400 mesh 100/pk

Quantifoil R 10/10 ; Gold 400 Mesh 100/pk

M-CEM-Q4100AR1010 100 GRIDS
EUR 1000
Description: Quantifoil R 10/10 ; Gold 400 Mesh 100/pk

Quantifoil R 10/20; Gold 400 Mesh 100/pk

M-CEM-Q4100AR1020 100 GRIDS
EUR 1000
Description: Quantifoil R 10/20; Gold 400 Mesh 100/pk

Quantifoil R 10/5; Gold 400 Mesh 100/pk

M-CEM-Q4100AR105 100 GRIDS
EUR 1000
Description: Quantifoil R 10/5; Gold 400 Mesh 100/pk

Quantifoil R 17/5; Gold 400 Mesh 100/pk

M-CEM-Q4100AR175 100 GRIDS
EUR 1000
Description: Quantifoil R 17/5; Gold 400 Mesh 100/pk

Quantifoil R 2/2 ; Gold 400 Mesh 100/pk

M-CEM-Q4100AR2 100 GRIDS
EUR 925
Description: Quantifoil R 2/2 ; Gold 400 Mesh 100/pk

Quantifoil R 1.2/2.5 ; Gold 400 Mesh 100/pk

M-CEM-Q4100AR2.5 100 GRIDS
EUR 825
Description: Quantifoil R 1.2/2.5 ; Gold 400 Mesh 100/pk

Quantifoil R 1.2/20; Gold 400 Mesh 100/pk

M-CEM-Q4100AR21.2 100 GRIDS
EUR 825
Description: Quantifoil R 1.2/20; Gold 400 Mesh 100/pk

Quantifoil R 3/3; Gold 400 Mesh 100/pk

M-CEM-Q4100AR3 100 GRIDS
EUR 925
Description: Quantifoil R 3/3; Gold 400 Mesh 100/pk

Quantifoil R 2/4 ; Gold 400 Mesh 100/pk

M-CEM-Q4100AR4 100 GRIDS
EUR 925
Description: Quantifoil R 2/4 ; Gold 400 Mesh 100/pk

Quantifoil R 3/5; Gold 400 Mesh 100/pk

M-CEM-Q4100AR5 100 GRIDS
EUR 925
Description: Quantifoil R 3/5; Gold 400 Mesh 100/pk

Quantifoil R 5/10; Gold 400 Mesh 100/pk

M-CEM-Q4100AR510 100 GRIDS
EUR 895
Description: Quantifoil R 5/10; Gold 400 Mesh 100/pk

Quantifoil R 6/100; Gold 400 Mesh 100/pk

M-CEM-Q4100AR6100 100 GRIDS
EUR 1000
Description: Quantifoil R 6/100; Gold 400 Mesh 100/pk

Quantifoil R 6/6.5; Gold 400 Mesh 100/pk

M-CEM-Q4100AR665 100 GRIDS
EUR 1000
Description: Quantifoil R 6/6.5; Gold 400 Mesh 100/pk

Quantifoil R 1/2 ; Nickel 400 Mesh 100/pk

M-CEM-Q4100CR-12 100 GRIDS
EUR 718
Description: Quantifoil R 1/2 ; Nickel 400 Mesh 100/pk

Quantifoil R 2/1 ; Copper 400 Mesh 100/pk

M-CEM-Q4100CR1 100 GRIDS
EUR 710
Description: Quantifoil R 2/1 ; Copper 400 Mesh 100/pk

Quantifoil R 10/10 ; Copper 400 Mesh 100/pk

M-CEM-Q4100CR1010 100 GRIDS
EUR 895
Description: Quantifoil R 10/10 ; Copper 400 Mesh 100/pk

Quantifoil R 10/20; Copper 400 Mesh 100/pk

M-CEM-Q4100CR1020 100 GRIDS
EUR 895
Description: Quantifoil R 10/20; Copper 400 Mesh 100/pk

Quantifoil R 10/5; Copper 400 Mesh 100/pk

M-CEM-Q4100CR105 100 GRIDS
EUR 895
Description: Quantifoil R 10/5; Copper 400 Mesh 100/pk

Quantifoil R 17/5; Copper 400 Mesh 100/pk

M-CEM-Q4100CR175 100 GRIDS
EUR 895
Description: Quantifoil R 17/5; Copper 400 Mesh 100/pk

Quantifoil R 2/2 Copper 400 Mesh 100/pk

M-CEM-Q4100CR2 100 GRIDS
EUR 650
Description: Quantifoil R 2/2 Copper 400 Mesh 100/pk

Quantifoil R 1.2/1.3 ; Copper 400 Mesh 100/pk

M-CEM-Q4100CR2.5 100 GRIDS
EUR 718
Description: Quantifoil R 1.2/1.3 ; Copper 400 Mesh 100/pk

Quantifoil R 1.2/20; Copper 400 Mesh 100/pk

M-CEM-Q4100CR21.2 100 GRIDS
EUR 718
Description: Quantifoil R 1.2/20; Copper 400 Mesh 100/pk

Quantifoil R 2/4 ; Copper 400 Mesh 100/pk

M-CEM-Q4100CR4 100 GRIDS
EUR 700
Description: Quantifoil R 2/4 ; Copper 400 Mesh 100/pk

Quantifoil R 3/5; Copper 400 Mesh 100/pk

M-CEM-Q4100CR5 100 GRIDS
EUR 718
Description: Quantifoil R 3/5; Copper 400 Mesh 100/pk

Quantifoil R 5/10; Copper 400 Mesh 100/pk

M-CEM-Q4100CR510 100 GRIDS
EUR 718
Description: Quantifoil R 5/10; Copper 400 Mesh 100/pk

Quantifoil R 6/100; Copper 400 Mesh 100/pk

M-CEM-Q4100CR6100 100 GRIDS
EUR 895
Description: Quantifoil R 6/100; Copper 400 Mesh 100/pk

Quantifoil R 6/6.5; Copper 400 Mesh 100/pk

M-CEM-Q4100CR665 100 GRIDS
EUR 895
Description: Quantifoil R 6/6.5; Copper 400 Mesh 100/pk

Quantifoil R 2/1 ; Nickel 400 Mesh 100/pk

M-CEM-Q4100NR1 100 GRIDS
EUR 749
Description: Quantifoil R 2/1 ; Nickel 400 Mesh 100/pk

Quantifoil R 1.2/1.3; Nickel 400 Mesh 100/pk

M-CEM-Q4100NR1.3 100 GRIDS
EUR 785
Description: Quantifoil R 1.2/1.3; Nickel 400 Mesh 100/pk

Quantifoil R 10/10 ; Nickel 400 Mesh 100/pk

M-CEM-Q4100NR1010 100 GRIDS
EUR 970
Description: Quantifoil R 10/10 ; Nickel 400 Mesh 100/pk

Quantifoil R 10/20; Nickel 400 Mesh 100/pk

M-CEM-Q4100NR1020 100 GRIDS
EUR 970
Description: Quantifoil R 10/20; Nickel 400 Mesh 100/pk

Quantifoil R 10/5; Nickel 400 Mesh 100/pk

M-CEM-Q4100NR105 100 GRIDS
EUR 970
Description: Quantifoil R 10/5; Nickel 400 Mesh 100/pk

Quantifoil R 17/5; Nickel 400 Mesh 100/pk

M-CEM-Q4100NR175 100 GRIDS
EUR 970
Description: Quantifoil R 17/5; Nickel 400 Mesh 100/pk

Quantifoil R 2/2 ; Nickel 400 Mesh 100/pk

M-CEM-Q4100NR2 100 GRIDS
EUR 705
Description: Quantifoil R 2/2 ; Nickel 400 Mesh 100/pk

Quantifoil R 1.2/20; Nickel 400 Mesh 100/pk

M-CEM-Q4100NR21.2 100 GRIDS
EUR 812
Description: Quantifoil R 1.2/20; Nickel 400 Mesh 100/pk

Quantifoil R 3/3; Nickel 400 Mesh 100/pk

M-CEM-Q4100NR3 100 GRIDS
EUR 812
Description: Quantifoil R 3/3; Nickel 400 Mesh 100/pk

Quantifoil R 2/4 ; Nickel 400 Mesh 100/pk

M-CEM-Q4100NR4 100 GRIDS
EUR 800
Description: Quantifoil R 2/4 ; Nickel 400 Mesh 100/pk

Quantifoil R 3/5; Nickel 400 Mesh 100/pk

M-CEM-Q4100NR5 100 GRIDS
EUR 812
Description: Quantifoil R 3/5; Nickel 400 Mesh 100/pk

Quantifoil R 5/10; Nickel 400 Mesh 100/pk

M-CEM-Q4100NR510 100 GRIDS
EUR 812
Description: Quantifoil R 5/10; Nickel 400 Mesh 100/pk

Quantifoil R 6/100; Nickel 400 Mesh 100/pk

M-CEM-Q4100NR6100 100 GRIDS
EUR 970
Description: Quantifoil R 6/100; Nickel 400 Mesh 100/pk

Quantifoil R 6/6.5; Nickel 400 Mesh 100/pk

M-CEM-Q4100NR665 100 GRIDS
EUR 970
Description: Quantifoil R 6/6.5; Nickel 400 Mesh 100/pk

Mechanical tests for samples of multi-uhmwpe cylinder shapes, made of porous uhmwpe as a trabecular layer and armored layer (cortical layer) consisting of bulk films and UHMWPE, shows an increase in the mechanical properties of all types of glue, as a result of the existence of the UHMWPE film and Increased number of layers. The strength of the maximum press yield and modulus value of the press for the armored layer (bulk and six layers of UHMWPE film using glue based on the Tiol-ENE reaction) is 44.1 MPa (a 1730 mpa increase (increasing 36%), compared to one layer uhmwpe steel Joint reconstruction.

 

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